Amph Most powerful comic book villains

The Beyonder, although he wasnt technically a villian, just an amoral being.

 

The Saint of Killers from Preacher. I can't believe I forgot about him.

If you want power, he's got it in spades. Guns that never miss and never run out of ammo. Every shot it a kill, never any injuries. And he's tough. They dropped a nuke on him and he just stood that and spat.

God for that matter might be considered a villain in Preacher.

 

smart/crazy ones come from DC...
Doom and Thanos are both from Marvel. They just happen to be smart, mentally warped, and incredibly powerful.

 

DC: Darkside & Lex

Marvel: Magneto, Thanos, and Apocolypse.

If I had to pick one, I would say Darkside. He is a match for Superman in strength, and is smart. He also survived an attack by Doomsday.

 

Magneto, Lex Luthor, Dark Phoenix, Doomsday, and many more

 

Well, for ones not mentioned yet. How about Mister Sinister?